Archive for the 'supplements' Category

The War Against Superbugs

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In the 1960’s, who had ever heard of superbugs? Antibiotics were once the “silver bullet” for fighting infectious bacteria. But bacteria have evolved, and our antibiotics haven’t caught up. Find out why, and how we’re taking on superbugs and antibiotic resistance in the Infectious Diseases group at the Novartis Institutes for BioMedical Research.

© 2015 Novartis AG

Attack of the Super Bugs

Don’t panic! But you should really know about antibiotic-resistant bacteria, aka super bugs. They’re here, and they’re doing very well, thank you. SciShow explains what they are, how they’re getting around our best drugs, and what science (and you) can do to help.
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Sources:
http://phenomena.nationalgeographic.com/2011/08/31/bacteria-resisting-antibiotics-for-at-least-30000-bc/
http://www.wired.com/wiredscience/superbug
http://www.oxfordjournals.org/our_journals/jpids/prpaper.pdf
http://www.cdc.gov/getsmart/antibiotic-use/antibiotic-resistance-faqs.html
http://www.scientificamerican.com/article/how-do-antibiotics-kill-b/
http://health.howstuffworks.com/medicine/medication/question88.htm
http://www.pbs.org/wgbh/aso/databank/entries/dm28pe.html
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1945/fleming-bio.html
https://www.youtube.com/watch?v=RpKZvnJwicA CDC ad
https://www.youtube.com/watch?v=ikZQPB45Zbw — Karl Klose TED talk
http://www.cdc.gov/getsmart/campaign-materials/print-materials/Brochure-general-color.pdf
http://www.livescience.com/43301-explainer-what-is-a-virus.html
http://www.microbeworld.org/types-of-microbes/bacteria
http://uhavax.hartford.edu/bugl/histepi.htm
http://science.nationalgeographic.com/science/health-and-human-body/human-diseases/plague-article/
http://www.huffingtonpost.com/tim-fothergill-phd/superbugs_b_4709723.html
http://www.bioexpress.ac.cn/upload/20110916-nature10388.pdf
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC90351/
http://www.mayoclinic.org/healthy-living/consumer-health/in-depth/antibiotics/art-20045720
http://www.idsociety.org/Index.aspx
http://www.washingtonpost.com/opinions/resistance-to-antibiotics-is-becoming-a-crisis/2012/07/10/gJQAFwFfbW_story.html
http://www.huffingtonpost.com/tim-fothergill-phd/antibiotic-research_b_4784234.html
http://cid.oxfordjournals.org/content/early/2013/04/16/cid.cit152.full
http://www.scientificamerican.com/article/swapping-germs/
http://www.mayoclinic.org/medical-professionals/clinical-updates/digestive-diseases/quick-inexpensive-90-percent-cure-rate – fecal transplant
http://www.sciencedaily.com/releases/2011/06/110608093745.htm
http://www.sciencedaily.com/releases/2012/03/120326113626.htm
http://www.healthline.com/health-news/tech-two-new-techniques-to-fight-bacteria-without-antibiotics-101813
http://oregonstate.edu/ua/ncs/archives/2013/oct/beyond-antibiotics-%E2%80%9Cppmos%E2%80%9D-offer-new-approach-bacterial-infection -PPMO *
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278648/ — phage*
http://www.popsci.com/science/article/2011-11/bacteria-swap-gene-information-through-global-network
http://newsoffice.mit.edu/2011/hgt-bacteria-1031
http://science.howstuffworks.com/environmental/life/cellular-microscopic/question561.htm
http://www.evolution-of-life.com/en/observe/video/fiche/mutations-selection-the-bacteria-resist.html
http://www.ncbi.nlm.nih.gov/books/NBK21942/
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Superbugs Moving From Hospitals to Homes

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A superbug gets its power from the ability to mutate. Developing resistance to common antibiotics. A long-standing concern for hospitals and nursing homes, drug resistant MRSA can cause pneumonia and bloodstream infections.

“Nowadays there’s a lot of vigilance about hospital-acquired infection. So hospitals are paying a lot of attention in making sure that people who come to our hospital to get better, we don’t give them an infection,” says Dr. Pranav Shah, an infectious disease specialist with Lee Memorial Health System.

Starting in the late 80s, MRSA hit the community at-large. Causing skin infections, some of them life-threatening. Spread through skin-to-skin contact, athletes and people living in close quarters were most at risk.

“The first outbreak of MRSA was in a NFL football team where they got MRSA because they were sharing in the locker room. And then it came through to the regular population as well,” says Dr. Shah.

From hospitals to homes, MRSA is still adapting. Studies find it now taking up residence in private homes. The CDC estimates 2 in every 100 people are colonized with MRSA, without sickness. As smart as this bug is-m preventing its spread is relatively simple.

“The best thing you can do is hand washing. Hand washing, hand washing, hand washing. That’s all, that’s the best way of preventing you from getting MRSA infection,” says Dr. Shah.

Cleanliness, both careful cleaning and covering open cuts, should keep a damaging bug at arm’s length.

View More Health Matters video segments at leememorial.org/healthmatters/

Lee Memorial Health System in Fort Myers, FL is the largest network of medical care facilities in Southwest Florida and is highly respected for its expertise, innovation and quality of care. For nearly a century, we’ve been providing our community with everything from primary care treatment to highly specialized care services and robotic assisted surgeries.

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Falling In Reverse – "Drugs"

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“Drugs” by Falling In Reverse
Listen on Spotify: https://spoti.fi/2UlGdQF
Listen on Apple Music: https://apple.co/2UmlDje

Lyrics

Kill yourself is what they said to me
I’m already dead Just differently
They say god is real, I disagree.
Cause if that were true, then we’d all be free (yeah)
Running from somethin that’s killin me dealin
With such an uncomfortable feelin beginning to feel the hostility from my ability of slowly becomin the villain
I just wanna thank all my fans especially
Without you is the death of me
I don’t consider myself a celebrity
But I’ll be doin this shit till I’m 70
This is my destiny
This is the best of me
It’s an incredible feeling to
Grow letting it go I’m letting you know
We are killin ourselves on the low

Everybody wants some
Everybody gets none from me

Cause Everybody’s on drugs
It’s hard to believe
The American dream
Is a killing machine
We’re all falling in love
With a new disease
And if it’s killing you
Then it’s murdering me
It’s all getting so
Unbelievable
We’re having so much fun
Staring down a loaded gun
And you don’t see that it’s killing you
Cause everybody’s on drugs

Save yourself is what I’m telling you,
Cause nobody else, really has a clue
Into your veins, like heroin.
Accept the pain
Just to feel again

Everybody wants some
Everybody gets none from me

Cause Everybody’s on drugs
It’s hard to believe
The American dream
Is a killing machine
We’re all falling in love
With a new disease
And if it’s killing you
Then it’s murdering me
It’s all getting so
Unbelievable
We’re having so much fun
Staring down a loaded gun
And you don’t see that it’s killing you
Cause everybody’s on drugs

Everybody is dead from the
Neck up
Tryin to keep their heads up
Searchin for a way out
This is a dying nation
So complacent
Our spirits need awakened
What are we waiting for

Die mother fucker, die motherfucker die!

Everybody’s on drugs
The American dream is a killing machine
Everybody’s on drugs
And it’s killing you.
It’s so fucking,
Unbelievable
We’re having so much fun staring
Down a loaded gun
And you don’t see that it’s killing you
Cause Everybody’s on drugs

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#fallinginreverse #drugs #epitaph
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A mom of four living on the streets and abusing drugs lets cameras follow her for a day. How does her family react after getting a glimpse into her life?

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Dr. Phil uses the power of television to tell compelling stories about real people.

The Dr. Phil show provides the most comprehensive forum on mental health issues in the history of television. For over a decade, Dr. McGraw has used the show’s platform to make psychology accessible and understandable to the general public by addressing important personal and social issues. Using his top-rated show as a teaching tool, he takes aim at the critical issues of our time, including the “silent epidemics” of bullying, drug abuse, domestic violence, depression, child abuse, suicide and various forms of severe mental illness.
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Blister Machine, packaging for pharmaceuticals in Thailand

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Blister Packaging Machine running in pharmaceutical factory in Thailand.
http://www.jornen.com/blister-machines/
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In this video, Strategy& thought leaders explain how pharma companies are responding to commercial model challenges, and how they must adapt their sales and marketing approaches to thrive
in the future.
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Lessons From Synergy Pharmaceuticals Stock's Disastrous Fall

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Synergy Pharmaceuticals (NASDAQ: SGYP) beat the odds by successfully winning FDA approval of Trulance last year, but it may not matter. Recently, management warned its struggling to renegotiate its debt and that increases the risk of its bankruptcy.

In this clip from The Motley Fool’s Industry Focus: Healthcare, host Shannon Jones is joined by Motley Fool contributor Todd Campbell to discuss what’s going on and more importantly, lessons biotech investors can learn to spot high-risk companies like this in the future.
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Considering a career in the pharmaceutical industry?

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Roger offers advice to students considering a career in pharmaceuticals about what they need to know about the industry, the latest development around the world and in the UK, and how students can keep up to date with the latest news – essential for success during a job interview.
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Packaging Of Pharmaceuticals |Pharmacy Online Lecture-2 | Pharmaceutics-Ch-2 | In Hindi | हिंदी में

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Hello Friends , here is the next video in the learning pharmacy series….

In this video , we have discussed about Pharmacy Online Lecture | Pharmaceutics-Ch-1 | Dosage Forms Of The Drugs I In Hindi | हिंदी में

We tried to prepare the best content for you so watch the video until the end.

#GPAT #NIPER #DRUG #INSPECTOR #Pharmacy #competitive #Exams

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Topic discussed in the video :-
1-Introduction & Function
2-Types Of Packaging
3-Materials Used In Pharmaceutical Packaging

1-Introduction Of Packaging
Packaging is a science, art & technology of enclosing or protecting products for distribution, storage, sale & use.

Pharmaceutical packaging is the economical means of providing protection, identification, information, convenience and stability of the product.

2-Functions / Benefits Of Packaging
Product identification- Packaging greatly helps in identification of the products.

Product protection- Packaging protect the content of the product from spoilage, breakage, leakage.

Facilitate the use of product- Packaging makes product convenient to open, handle and use by the consumer.

Product promotion- Packaging helps in product promotion & attract the attention of the people while purchasing.

3-Types Of Packaging
Primary Packaging
Is the material that first envelops the product and hold it.

Secondary Packaging
Is outside the primary packaging, used to group primary package together.

Tertiary Packaging
Is used for bulk handling & shipping.

4-Material used in Packaging
Glass
Plastic
Rubbers
Paper/cardboard
Metals

A-Glass As Packaging Material
Advantage
They are transparent
Economical
Easily labelled
Have good protection power
Available in variety of shapes & sizes.

Disadvantage
Glass is fragile so easily broken
Release alkali to preparation

Composition Of Glass
*Silicon di-oxide/ Sand Sio2 72%
*Sodium Oxide(Na2O) From Sodium Carbonate Na2CO3 (soda ash) 13%
*Calcium Oxide/Lime CaO 12%
*Aluminum Oxide Al2O3 2%
*Minors 1%

b-Plastic As Packaging Material
Plastics are group of substance of natural or synthetic origin, consisting chiefly of the polymers of high molecular weight that can be molded into a shape by means of heat & pressure.

Advantage
Less weight than glass
Flexible
Variety of shape & size
Resistant to breakage
Chemically inert, safe in use
Disadvantage
Absorption permeability to moisture
Poor printing property
Types Of Plastics
Thermoplastic Type
On heating, become soften to viscous fluid which harden again on cooling.

Examples- Polypropylene, polystyrene, cellulose acetate, PTFE (Teflon), nylon, polyketone, etc.

Thermosetting Type
On heating, irreversibly to become hard at high temperature and remain in a permanent solid state once hardened.

Examples- epoxy resin, melamine formaldehyde, polyester resin and urea formaldehyde.

Metal As Packaging Material
Metals are used for preparation of containers. The metals commonly used are aluminum, tin plated steel, stainless steel, tin and lead.
Advantage
Impermeable to light, moisture & gas
Rigid & Unbreakable
Light in weight than glass Container
Label can be printed directly Onto the surface

Disadvantage
Expensive
May react with certain chemicals

Rubber As Packaging Material
Rubber is mainly used for construction of closures for vials, transfusion fluid bottles, dropping bottles and for many other type of products.
Types Of Rubbers
Butyl Rubber
Nitrile Rubber
Neoprene Rubber
Silicon Rubber

Paper And Cardboards
Paper & Cardboards are suitable for small scale and bulk packaging, also suitable for all kinds of food packaging.
Advantage
Light weight
Less expensive & Easily available
Cardboard cartons have high shock resistant capacity

Disadvantage
May cause damage on transportation without external barriers
Most paper packs are not reusable

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Background music of the video –
Dream Culture by Kevin MacLeod is licensed under a Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/)
Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1300046
Artist: http://incompetech.com/
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Big Pharma Big Money : Documentary on the Money and Corruption of Big Pharmaceutical Companies

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Big Pharma Big Money : Documentary on the Money and Corruption of Big Pharmaceutical Companies.

You are really going to enjoy this documentary. It’s very interesting and fun to watch. It’s part of a series of exciting and informative documentaries. This Youtube channel is for learning and educational purposes. Learning and Education are fundamental and important in today’s society and becoming increasingly more accessible and convenient online. The availability of important information which is also entertaining helps everyone grow mentally and emotionally as people both individually and as a whole. Documentaries are the resource of choice of the information and internet generations of students around the world. The documentary here along with the other documentaries on this channel relate to important times and people in history, historic places, archaeology, society, world culture, science, conspiracy theories, and education.
The topics covered in these video documentaries vary and cover about everything you could possibly want to know including ancient history, Maya, Rome, Greece, The New World, Egypt, World wars, combat, battles, military and combat technology, current affairs and events, important news, Social Studies, education, biographies, famous people and celerities, politicians, news and current events, Illuminati, Area 51, crime, mafia, serial killers, paranormal, supernatural, cults, government cover-ups, the law and legal matters, corruption, martial arts, sports figures, space, aliens, ufos, conspiracy theories, Annunaki, Nibiru, Nephilim, satanic rituals, religion, christianty, judaism, islam, strange phenomenon, origins of Mankind, Neanderthal, Cro Magnon, Inca, Aztec, Persia, Maya, Indus, Mesopotamia, monsters, mobsters, time travel, planet earth, the Sun, Missions to Mars, The planets, the solar system, the universe, modern physics, String Theory, the Big Bang Theory, Quantum Mechanics, television, archaeology, science, technology, nature, plants, animals, endangered species, wildlife, animal abuse, environmental concerns and issues, global warming, natural disasters, racism, sexism, LGBT, gay and lesbian issues, and many other educational and controversial topics. Please enjoy and Learn Responsibly!

WATCH LIVE: Top pharmaceutical executives testify before the Senate Finance Committee on drug prices

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15 Things You Didn't Know About The Pharmaceutical Industry

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15 Things You Didn’t Know About The Pharmaceutical Industry | Industry Wednesday
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Is Pfizer the largest pharmaceutical company in the world?
Is GSK the largest pharmaceutical company?
How much money is spent per year on prescription drugs?
Who discovered the drug?
How much does the pharmaceutical industry spend on marketing?
How much money is spent on prescription drugs each year?
What countries allow drug companies to advertise?
Who invented the first antibiotic?
Do supplements make you thirsty?
How much does it cost to make a new drug?

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Want to be a drug addict? If you live in the U.S. chances are you probably already are. The U.S. – land of the free, of MTV, and of legal drugs. This might just be what makes America great. A place where our doctors prescribe us pills we don’t need for conditions that don’t exist. It’s a win-win. Big Pharma gets bigger and richer and we get higher or just die.

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Music: FloFilz – Tilezeit

The story was different 50 years ago when Jon went down to his dentist’s office to get his wisdom teeth pulled and the doctor gave him aspirin as pain medication. This was a time when young men went to war and women worked their asses off at home to save the country from collapse. Now? We get high, play video games, watch YouTube, and complain when someone doesn’t call us the right gender. And these days if old Jonny boy goes to the dentist and wants some work done it’s dealers choice. Vicodin. Percocet. Codeine. You name it. Whatever company happens to be in bed with your doctor that day. And if you don’t have private insurance that pays for your drugs? No problem. Sign up for Medicaid. You’ll definitely be able to get free drugs through them.

First what exactly is the pharmaceutical industry? To make a long story short it’s a business that creates drugs for use as medications. It’s important to note that it’s not a terrible industry. In fact they have made some very important discoveries like insulin which has saved millions of lives or the countless vaccines that have protected us from at one point, very common diseases like measles and hepatitis.

The problem is not the idea of pharmaceuticals – drugs are neither good nor bad. They can either be helpful or dangerous depending on their use. The problem with big pharma is that it is literally killing people. And it’s making a profit doing so. And our government is basically encouraging it.

You may ask yourself how an industry that it supposed to be providing us medication which is regulated by the Federal Drug Administration – an organization responsible for “protecting the public health by assuring the safety, efficacy and security of human…drugs,” is killing us. Let’s first look at the health statistics:

• 99% of hydrocodone worldwide use is in the U.S – we know this drug more colloquially as Vicodin (which is just a company that makes hydrocodone). This is a drug that the FDA rates as less dangerous as marijuana but in 2011 caused nearly 100,000 emergency department visits.
• The U.S. makes up 5% of the world’s population but consumes 80% of its opioid consumption
• On average 40 deaths per day are linked to specifically prescription opioids and over 100,000 deaths per year linked with prescription drugs in general. This is far more deaths than what illegal street drugs cause.
• Prescription drugs are now the 4th leading cause of death in the U.S.

Ok. You get the point. Prescription drugs are dangerous and they are killing people. But now the question is why are people taking them if they’re so dangerous? The answer lies in the incredible reach of big Pharma. The pharmaceutical industry spends between 30 and 60 billion dollars a year on advertising their miracle drugs. You’ve all seen their ads – blue skies, beautiful couple, trees – having trouble sleeping? Bad knees? Buy our pill and feel like new. And then the 10 second list of possible side effects which always include “and in extreme cases, death.” The folks that regulate these advertisements have a budget of million dollars. Do you really think a million dollar budget is enough to regulate something that is more than 6,000 times that size. This is not a David vs. Goliath story. This is an ant vs. an elephant.

Big pharma is also notorious for selling drugs that aren’t approved for certain symptoms – a practice called Off-Label Promotion. For example your doctor might prescribe you an antidepressant because she or he believes it will help your migraines. This practice is at times is legal and at others illegal. If illegal you will learn shortly that the fine usually is smaller than the profit these companies make. Big pharma might just consider it another tax of doing business. And yes it has in some cases caused death.

There is also the idea that big Pharma creates new illnesses and solves them with their pills. Sounds like a conspiracy theory, right? But actually it makes a lot of sense and you’ve probably seen an ad that talks about some made up illness and a pill to fix it without thinking twice. For example restless leg syndrome. Is that really an illness?
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